Lab of Molecular Pathobiology

The overall mission of our lab is to explore the pathogenesis and interactions of viral pathogens from various animal species, such as classical swine fever virus (CSFV), porcine reproductive respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), torque teno sus virus (TTSuV), porcine endemic diarrhea virus (PEDV), and feline infectious peritonitis virus (FIPV). Extending the aforementioned studies to vaccine developments such as PRRSV and PEDV, either by using traditional or plant-based delivery systems, is our principal task. Our lab is also involved in the anatomic pathology residency training program and the routine pathological diagnostic service; therefore, diagnosis and disease surveillance of important zoonotic and non-zoonotic pathogens, such as mycobacteria, hepatitis E virus, Nipah virus, rabies virus, chytrid fungus, Coxiella burnetii, or even toxicosis in wildlife and domestic animals are our research interests as well.
Faculty

Dr. Chian-Ren Jeng crjeng@ntu.edu.twT. +886 2 33663869

Dr. Hui-Wen Chang huiwenchang@ntu.edu.twT. +886 2 33669899

Dr. Yen-Chen Chang yenchenchang@ntu.edu.twT. +886 2 33663873

 Research interests

Dr. Chian-Ren Jeng

  1. Pathogenesis and interactions of porcine viral pathogens, including CSFV, PRRSV and PCV2
  2. Development of plat-based PRRSV oral vaccine,
  3. Diagnosis and disease surveillance of important zoonotic diseases, including tuberculosis, hepatitis E virus and Nipath virus

Dr. Hui-Wen Chang

  1. Molecular pathogenesis of viral diseases
  2. Subunit vaccine, inactive vaccine, or live attenuate vaccine development.
  3. Molecular virology: viral virulent gene determination, cellular receptor identification, viral-host interactions, and the epidemiology of viral diseases.

Dr. Yen-Chen Chang

  1. Immunopathogenesis of viral disease
  2. Subunit vaccine, inactive vaccine, or live attenuate vaccine development
  3. Protein structure and post-translational modifications of viral proteins
  4. Diagnosis and disease surveillance of animal diseases