Associate Professor Chen-Si Lin

Highest Degree: Ph.D., NCTU, ROC.

Research Area: Cancer Immunology and Microbiology

Tel: +886-2-3366-1286

Email: cslin100@ntu.edu.tw

Office hours: by appointment

Publications:
  • Journal papers

    1. (Equal First author) Liao KW, Lin CS, Chen WL, Yang CT, Lin CM, Hsu WT, Lin YY, Chiu YH, Huang KC, Wu MS, Mao SJT, Tsai NM. 2011. Antibodies against Helicobacter pylori heat shock protein 60 aggravate HSP60-mediated proinflammatory responses. [Cytokine accepted] (SCI 3.123; 108/283 in BIOCHEMISTRY & MOLECULAR BIOLOGY)

    2. Lin CS, Wang CL, Tsai HJ, Chou CH. 2010 Growth of Listeria monocytogenes on a RTE-meat matrix enhances cell invasiveness to Mouse J744A.1 macrophages. International Journal of Food Microbiology. 144:199-201. (SCI 3.011; 8/118 in FOOD SCIENCE & TECHNOLOGY)

    3. Lin CS, Chion WY, Cheun LL, Shieh LE, Chu, RM. 2010, Deterioration and metastasis of a canine transmissible venereal tumor in a dog associated with a CPV-2. Taiwan Vet J. 36(3): 191-199

    4. Lin CS, He PJ, Hsu WT, Wu MS, Wu CJ, Shen HW, Hwang CH, Lai YK, Tsai NM, Liao KW., 2010, Helicobacter pylori-derived Heat shock protein 60 enhances angiogenesis via a CXCR2-mediated signaling pathway, Biochem Biophys Res Commun. 25;397(2):283-9. (SCI 2.548; 146/283 in BIOCHEMISTRY & MOLECULAR BIOLOGY)

    5. Lin CS, He PJ, Tsai NM, Li CH, Yang SC, Hsu WT, Wu MS, Wu CJ, Cheng TL, Liao KW., 2010, A potential role for Helicobacter pylori heat shock protein 60 in gastric tumorigenesis., Biochem Biophys Res Commun, 392(2):183-9. (SCI 2.548; 146/283 in BIOCHEMISTRY & MOLECULAR BIOLOGY)

    6. Lin CY, Huang YS, Li CH, Hsieh YT, Tsai NM, He PJ, Hsu WT, Yeh YC, Chiang FH, Wu MS, Chang CC, Liao KW., 2009, Characterizing the polymeric status of Helicobacter pylori heat shock protein 60., Biochem Biophys Res Commun. 388(2):283-9. (SCI 2.548; 146/283 in BIOCHEMISTRY & MOLECULAR BIOLOGY)

    7. Lin CY, Chuang TF, Liao KW, Huang YJ, Pai CC, Chu RM., 2008, Combined immunogene therapy of IL-6 and IL-15 enhances anti-tumor activity through augmented NK cytotoxicity., Cancer Lett. 272(2):285-95. (SCI 3.741; 52/166 in ONCOLOGY)

    8. Yu WY, Chuang TF, Guichard C, El-Garch H, Tiemy D, Liao AT, Lin CS, Liu CH, Li WC, Fuscher L, Chu RM. 2011. Chicken HSP70 DNA vaccine inhibits tumor growth in a canine cancer model. Vaccine 29(18): 3489-500. (SCI 3.572; 25/106 in MEDICINE, RESEARCH & EXPERIMENTAL)

    9. Pai CC, Kuo TF, Mao SJT, Chuang TF, Lin CS, Chu RM. 2010, Immunopathogenic behaviors of canine transmissible venereal tumor in dogs following an immunotherapy using dendritic/tumor cell hybrid. Veterinary Immunology and Immunotherapy. (SCI 1.963; 14/142 in VETERINARY SCIENCES)

    10. Lin YL, Chen YS, Hsieh JH, Kin CM, Wu HY, Lin CS, Chu RM, Lioa KW, Hsu YH. 2010, Utilization of IκB-EGFP chimeric gene as an indicator to identify microbial metabolites with NF-κB inhibitor activity. Biological Procedures Online accepted. (SCI 0.75; 60/67 in BIOCHEMICAL RESEARCH METHODS)

    11. Li CH, Lee, RP, Lin YL, Lin CS, Hsu BG, Jen TF, Chen YC, Liao KW, Yang FL. 2010, The treatment of propofol induced the TGF-β1 expression in human endothelial cells to suppress endocytosis activities of monocytes. Cytokine 2010 Dec;52(3):203-9. (SCI 3.123; 108/283 in BIOCHEMISTRY & MOLECULAR BIOLOGY)

    12. Liu CC, Wang YS, Lin CY, Chuang TF, Liao KW, Chi KH, Chen MF, Chiang HC, Chu RM., 2008, Transient downregulation of monocyte-derived dendritic-cell differentiation, function, and survival during tumoral progression and regression in an in vivo canine model of transmissible venereal tumor., Cancer Immunol Immunother. 2008 Apr;57(4):479-91. (SCI 3.791; 32/128 in IMMUNOLOGY)

    13. Wu MS, Lin JT, Hsu PN, Lin CY, Hsieh YT, Chiu YH, Hsueh PR, Liao KW.. 2007. Preferential induction of transforming growth factor-beta production in gastric epithelial cells and monocytes by Helicobacter pylori soluble proteins.. J Infect Dis. 196(9):1386-93. (SCI 5.865; 4/57 in INFECTIOUS DISEASES)

    14. Chu RM, Lin CY, Liu CC, Yang SY, Hsiao YW, Hung SW, Pao HN, Liao KW. Proliferation characteristics of canine transmissible venereal tumor. Anticancer Res 2001 Nov-Dec;21(6A):4017-24. (SCI 1.428; 126/166 in ONCOLOGY)

  • Conference papers

    1. Hong-Rong Lei, Cheng-Se Lin, Chen-Si Lin, Chien-Yueh Lee, Lih-Seng Yeh, Shih-Chieh Chang. 2009 Gene expression study on a highly aggressive canine transmissible venereal tumor of a NOD/SCID mice model. (8th Frontiers in Cancer Prevention research)

    2. Ching-Yi Lin, Wei-Tung Hsu, Hsiao-Wei Shen, Kuang-Wen Liao. 2009 Characterizing the role f Helicobacter pylori heat shock protein 60 in activating transforming growth factor-β signal pathway. (17th Symposium on Recent Advances in Cellular and Molecular Biology)

    3. Pei-Jiun He, Ching-Yi Lin, Wei-Tung Hsu. 2009 Heat shock protein 60 derived from Helicobacter pylori is associated with malignant progression of gastric tumor. (17th Symposium on Recent Advances in Cellular and Molecular Biology)

    4. Ching-Yi Lin, Yuan-Ting Hsieh, Chi-Han Lee, Yi-Yin Lin, Yu-Shan Huang, Ming-Shiang Wu, Kuang-Wen Liao. 2008 Helicobacter pylori heat shock protein 60 elicits the burst of transforming growth factor-beta 1 production from gastric epithelial cells and monocytes. (The 23rd Joint Annual Conference of Biomedical Sciences).

    5. Yuan-Ting Hsieh, Ching-Yi Lin, Yi-Yin Lin, Tzu-Hui Yang, Kuang-Wen Liao. 2008 The effect of Helicobacter pylori heat shock protein 60 on naïve T cells differentiation. (The 23rd Joint Annual Conference of Biomedical Sciences)

    6. Yi-Yin Lin, Ching-Yi Lin, Kuang-Wen Liao. 2008 Both transforming growth factor-beta 1 and proinflammatory cytokines are induced by Helicobacter pylori heat shock protein 60 to monocyte activities. (The 23rd Joint Annual Conference of Biomedical Sciences)

    7. Pei-Jiun He, Ching-Yi Lin, Kuang-Wen Liao. 2008 Helicobacter pylori heat shock protein 60 induces monocyte to produce angiogeneic factors. (The 23rd Joint Annual Conference of Biomedical Sciences)

    8. Yu-Shan Huang, Ching-Yi Lin, Yuan-Ting Hsieh, Kuang-Wen Liao. 2008 The role of Helicobacter pylori heat shock protein 60 structure in inducing transforming growth factor-beta production in gastric epithelial cells. (The 23rd Joint Annual Conference of Biomedical Sciences)

    9. Chu-Ting Yang, Tzu-Hui Yang, Ching-Yi Lin, Chi-Han Li, Kuang-Wen Liao. 2008 The effect of ALK signaling pathways on Hsp60s-induced cytokine expressions in THP-1 cells. (The 23rd Joint Annual Conference of Biomedical Sciences)

    10. Ching-Yi Lin, Yuan-Ting Hsieh, Chi-Han Lee, Yi-Yin Lin, Yu-Shan Huang, Ming-Shiang Wu, Kuang-Wen Liao. 2007 Helicobacter pylori heat shock protein 60 down-regulates monocytes activities by inducing transforming growth factor-beta 1 production in gastric epithelial cells. (Ninth NHRI Conference on Immunology).

    11. Kuang-Wen Liao, Yen-Ku Liu, Pei-Yun Chen, Ching-Yi Lin. 2007 DNA Shuffling technique for selecting active expressional promoter sequences. (Twenty-second Joint Annual Conference of Biomedical Science)

    12. Pei-Yun Chen, Yen-Ku Liu, Ching-Yi Lin, Kuang-Wen Liao. 2007 Finding promoter sequences with high activities of gene expression by DNA shuffling technique. (Fifteen Symposium on recent advances in cellular and molecular biology)

    13. Ching-Yi Lin, Yuan-Ting Hsieh, Ming-Shiang Wu, Jaw-Town Lin, Kuang-Wen Liao. 2007 Helicobacter pylori-derived soluble protein(s) induce the expression of transforming growth factor-beta. (Fifteen Symposium on recent advances in cellular and molecular biology)

    14. Ching-Yi Lin, Yuan-Ting Hsieh, Kuang-Wen Liao. 2006 Helicobacter pylori soluble proteins induce the expression of transforming growth factor-beta (2006 Symposium on Biotechnology in National Chiao-Tung University)

    15. 2002年 台灣省畜牧獸醫學會第二十一屆第二次會員大會暨中華民國獸醫學會第九屆90年度聯合年會學術論文口頭發表報告。發表題目:研究IL-6及IL-15對受腫瘤來源TGF-β抑制之NK細胞活性之影響。

    16. 2001年 台灣省畜牧獸醫學會第二十一屆第二次會員大會暨中華民國獸醫學會第九屆90年度聯合年會學術論文口頭發表報告。發表題目:以肌肉活體基因電衝導入IL-12基因以評估其對犬傳染性花柳性腫瘤之治療效果。

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