王家琪 副教授

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免疫毒理與動物用藥品安全評估實驗室（獸一館209室）

研究領域：皮膚致敏性替代試驗、免疫藥理及毒理、遺傳毒性

擔任課程：獸醫解剖學及實習、獸醫生理學、獸醫生理學實習

聯絡電話：Offie: 02-3366-1285 / Lab: 02-3366-3877

電子信箱：ccwang@ntu.edu.tw

研究論文連結：https://www.researchgate.net/profile/Chia-Chi_Wang2

學經歷：國立臺灣大學獸醫學博士

Office hours: 星期二 13:00-17:00 請同學先以Email方式與老師約定時間




近期學術著作：

  • 期刊論文：

  1. Yang J. L., C. Y. Chang, C. S. Sheng, C. C. Wang, and F. I. Wang. 2020. The tip region on VP2 protein of bluetongue virus contains potential IL-4-inducing amino acid peptide segments. Pathogens. 10(1): E3. (SCI)
  2. Kan H. L., C. C. Wang, Y. H. Cheng, C. L. Yang, H. S. Chang, I. S. Chen, and Y. C. Lin. 2020. Cinnamtannin B1 attenuates rosacea-like signs via inhibition of pro-inflammatory cytokine production and down-regulation of the MAPK pathway. PeerJ. 8: e10548. (SCI)
  3. Kan H. L., C. C. Wang, Y. C. Lin, and C. W. Tung. 2020. Computational identification of preservatives with potential neuronal cytotoxicity. Regul. Toxicol. Pharmacol. 119: 104815. (SCI)
  4. Wang C. C. , P. Lin, C. Y. Chou, S. S. Wang, and C. W. Tung. 2020. Prediction of human fetal-maternal blood concentration ratio of chemicals. PeerJ. 8: e9562. (SCI)
  5. Yang J. L., C. Y. Chang, W. C. Yen, L. H. Yen, C. C. Wang, and F. I. Wang. 2020. Type I hypersensitivity is induced in cattle PBMC during bluetongue virus Taiwan isolate infection. Vet. Immunol. Immunopathol. 226: 110071. (SCI)
  6. Liang P. I., C. C. Wang, H. J. Cheng, S. S. Wang, Y. C. Lin, P. Lin, and C. W. Tung. 2020. Curation of cancer hallmark-based genes and pathways for in silico characterization of chemical carcinogenesis. Database. 2020: baaa045. (SCI)
  7. Tung C. W., H. J. Cheng, C. C. Wang, S. S. Wang and P. Lin. 2019. Leveraging Complementary Computational Models for Prioritizing Chemicals of Developmental and Reproductive Toxicity Concern: An Example of Food Contact Materials. Arch. Toxicol. doi.org/10.1007/s00204-019-02641-0. (SCI)
  8. Chun-Wei Tung*, Chia-Chi Wang, Shan-Shan Wang, Pinpin Lin*. (2018). ChemDIS-Mixture: an online tool for analyzing potential interaction effects of chemical mixtures. Scientific Reports, 8: 10047.
  9. Chun-Wei Tung*, Chia-Chi Wang, Shan-Shan Wang. (2018). Mechanism-informed Read-across Assessment of Skin Sensitizers Based on SkinSensDB. Regulatory Toxicology and Pharmacology, 94: 276-282.
  10. Chung-Hsiung Huang, Chia-Chi Wang, Yu-Jin Lin, Masatoshi Hori, Tong-Rong Jan*. (2017). Oral administration with diosgenin enhances the induction of intestinal T helper 1-like regulatory T cells in a murine model of food allergy. International Immunopharmacology, 42(1): 59-66.
  11. Chia-Chi Wang, Ying-Chi Lin, Shan-Shan Wang, Chieh Shih, Yi-Hui Lin, Chun-Wei Tung*. (2017). SkinSensDB: a curated database for skin sensitization assays. Journal of Cheminformatics, 9:5.
  12. Chia-Chi Wang, Ying-Chi Lin, Yin-Hua Cheng, Chun-Wei Tung*. (2017). Profiling transcriptomes of human SH-SY5Y neuroblastoma cells exposed to maleic acid. PeerJ, 5: e3175.
  13. Chia-Chi Wang, Ying-Chi Lin, Yuan-Chung Lin, Syu-Ruei Jhang, Chun-Wei Tung. (2017). Identification of informative features for predicting proinflammatory potentials of engine exhausts. Biomedical Engineering Online, 16 (Suppl 1): 66.
  14. Yin-Hua Cheng, Ying-Chi Lin, Ih-Sheng Chen, Sian-De Liu, Jih-Heng Li*, and Chia-Chi Wang*. (2017). Immunomodulatory effects of Taiwanese Neolitsea species on Th1 and Th2 functionality. Journal of Immunology Research, Volume 2017, Article ID 3529859, 13 pages.
  15. Po-Ming Yang, Chia-Chi Wang, Ying-Chi Lin, Syu-Ruei Jhang, Li-Jung Lin, Yuan-Chung Lin*. (2017). Development of novel alternative biodiesel fuels for reducing PM emissions and PM-related genotoxicity. Environmental Research, 156:512-518.
  16. Yin-Hua Cheng, Ih-Sheng Chen, Ying-Chi Lin, Chun-Wei Tung, Hsun-Shuo Chang, Chia-Chi Wang*. (2016). Attenuation of antigen-specific T helper 1 immunity by Neolitsea hiiranensis and its derived terpenoids. PeerJ, 4: e2758.
  17. Chia-Chi Wang, Po-Wei Yang, Sheau-Fang Yang, Kun-Pin Hsieh, Sung-Pin Tseng, Ying-Chi Lin*. (2016). Topical Simvastatin Promotes Healing of Staphylococcus aureus-contaminated Cutaneous Wounds. International Wound Journal , 13(6): 1150-1157.
  18. Ying-Chi Lin, Chia-Chi Wang and Chun-Wei Tung*. An in silico toxicogenomics approach for inferring potential diseases associated with maleic acid. (2014). Chemico-Biological Interactions, 223(5): 38-44. (Co-first author).
  19. Chia-Chi Wang, Qingsu Xia, Meng Li, Shuguang Wang, Yuewei Zhao, William H. Tolleson, Jun-Jie Yin, Peter P. Fu* (2014). Metabolic Activation of Pyrrolizidine Alkaloids Leading to Phototoxicity and Photogenotoxicity in Human HaCaT Keratinocytes. Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology, 32(4): 362-384.
  20. Chin-Cheng Lee, Ying-Chi Lin, Hsingjin Eugene Liu, Tong-Rong Jan*, and Chia-Chi Wang*. (2014) Impairment of thymocyte function via induction of apoptosis by areca nut extract. Journal of Immunotoxicology, 11(2): 190-196.
  21. Chia-Chi Wang, Yu-Ru Lin, Mei-Hsiu Liao, Tong-Rong Jan*. (2013) Oral supplementation with areca-derived polyphenols attenuates food allergic responses in ovalbumin-sensitized mice. BMC Complementary and Alternative Medicine, 13:154.
  22. Chia-Chi Wang*, Shuguang Wang, Qingsu Xia, Weiwei He, Jun-Jie Yin, Peter P. Fu, Jih-Heng Li*. (2013). Phototoxicity of zinc oxide nanoparticles in HaCaT keratinocytes-generation of oxidative DNA damage during UVA and visible light irradiation. Journal of Nanoscience and Nanotechnology 13(6): 3880-3888.
  23. Chia-Chi Wang, Tz-Yu Chen, Tsung-Yun Liu, Tong-Rong Jan*. (2012). Areca nut extracts suppress the differentiation and functionality of human monocyte-derived dendritic cells. Journal of Periodontal Research, 47:198-203.
  24. Chia-Chi Wang, Ming-Chung Deng, Tong-Rong Jan*. (2011). Areca nut extracts attenuated interferon-γ and antigen-specific IgM production in BALB/c mice. Journal of Food and Drug Analysis, 19: 252-258.
  25. Chien-Chang Shen, Chia-Chi Wang, Mei-Hsiu Liao, Tong-Rong Jan*. (2011). A single exposure to iron oxide nanoparticles attenuates antigen-specific antibody production and T-cell reactivity in ovalbumin-sensitized BALB/c mice. International Journal of Nanomedicine, 6: 1229-1235.
  26. Chia-Chi Wang, Hung-Li Lin, Hong-Jen Liang, Tong-Rong Jan*. (2011). Areca nut extracts enhance the development of CD11b+Gr-1+ cells with the characteristics of myeloid-derived suppressor cells in antigen-stimulated mice. Journal of Oral Pathology & Medicine, 40:769-777.
  27. Chia-Chi Wang, Hung-Li Lin, Shiaw-Pyng Wey, Tong-Rong Jan*. (2010). Areca nut extract modulates antigen-specific immunity and augments inflammation in ovalbumin-sensitized mice. Immunopharmacology and Immunotoxicology, 33: 315-322.
  28. Chia-Chi Wang, Hsin-Ying Wu, Tong-Rong Jan*. (2010) The effect on animal growth and the impact on the environment by Roxarsone, an organic arsenic veterinary drug. Taiwan Veterinary Journal, 36: 115-123. (in Chinese)
  29. Chia-Chi Wang, Pei-Ling Huang, Tsung-Yun Liu, Tong-Rong Jan*. (2009) Highly oligomeric procyanidins from areca nut induce lymphocyte apoptosis via the depletion of intracellular thiols. Toxicology in Vitro, 23: 1234-41.
  30. Chia-Chi Wang, Tsung-Yun Liu, Chiung-Hsiang Cheng, Tong-Rong Jan*. (2009) Involvement of the mitochondrion-dependent pathway and oxidative stress in the apoptosis of murine splenocytes induced by areca nut extract. Toxicology in Vitro, 23: 840-7.
  31. Chia-Chia Wang, Tsung-Yun Liu, Shiaw-Pyng Wey, Fun-In Wang, Tong-Rong Jan*. (2007) Areca nut extract suppresses T-cell activation and interferon-γ production via the induction of oxidative stress. Food and Chemical Toxicology, 45: 1410-8.

     

2021/08/15 22:41

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