鄭益謙 教授

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獸醫臨床微生物及單源抗體研究室（獸一館311R）

研究領域：

  1. 以單源抗體(monoclonal antibody, MAb)為工具之口蹄疫(FMD)、豬水疱病(SVD)等動物水疱性疾病病毒預防醫學研究。目的：非結構蛋白抗體診 斷試劑、中和抗體檢測試劑之研發，及致病機制(pathogenesis)等之研究。
  2. 以融合瘤技術平臺與其它研究單位合作，研發針對動物病毒具特異性之MAb，進行疾病診斷、致病機制(pathogenesis)等研究。

擔任課程：獸醫遺傳學、反芻動物疾病學、免疫遺傳、豬病學

聯絡電話：（02）3366-9912

電子信箱：ivancheng@ntu.edu.tw

學歷：美國佛羅里達大學比較及實驗病理系博士

Office hours: 星期一14:00-17:00 （請同學先以Email方式與老師約定時間）

鄭益謙老師
    近期學術著作：

  • 期刊論文

  1. Tu Y. C., K. Y. Chen, C. K. Chen, M. C. Cheng, S. H. Lee, and I.C. Cheng*. 2019. Novel application of Influenza A virus-inoculated chorioallantoic membrane to characterize a NP-specific monoclonal antibody for immunohistochemistry assaying. J. Vet. Sci. 20(1):51-57. (SCI)
  2. Chang C. Y., I. C. Cheng, Y. C. Chang, P. S. Tsai, S. Y. Lai, Y. L. Huang, C. R. Jeng, V. F. Pang, and H. W. Chang*. 2019. Identification of Neutralizing Monoclonal Antibodies Targeting Novel Conformational Epitopes of the Porcine Epidemic Diarrhea Virus Spike Protein. Sci. Rep. 9(1):2529. (SCI)
  3. Liu I. L., Y. C. Lin, Y. C. Lin, C. Z. Jian, I.C. Cheng*, H. W. Chen. 2019. A Novel Immunochromatographic Strip for Antigen Detection of Avian Infectious Bronchitis Virus. Int. J. Mol. Sci. 20(9)2216. (SCI)
  4. Lee H. W., M. C. Deng, C. H. Pan, H. W. Chang, and I. C. Cheng. 2018. Neutralizing monoclonal antibodies against porcinophilic Foot-and-mouth disease virus mapped to antigenic site 2 by utilizing novel mutagenic virus-like particles to detect the antigenic change. Vet. Microbiol. 222:124–131. (SCI)
  5. Peng J. Y., C. Y. Chang, C. F. Kao, Y. C. Chang, C. S. Hsueh, C. R. Jeng, I. C. Cheng, V. F. Pang, P. S. Tsai, and H. W. Chang. 2018. Different intestinal tropism of the G2b Taiwan Porcine Epidemic Diarrhea virus-Pintung 52 strain in conventional 7-day-old piglets. Vet. J. 237:69-75. (SCI)
  6. Kao C. F., H. Y. Chiou, C. Y. Chang, C. S. Hsueh, C. R. Jeng, P. S. Tsai, I. C. Cheng, V. F. Pang, J. Y. Peng, and H. W. Chang. 2018：The characterization of immunoprotection induced by a cDNA clone derived from the attenuated Taiwan Porcine Epidemic Diarrhea Virus Pintung 52 strain. Viruses. 10(10):543-557（SCI）
  7. Chang Y. C., C. F. Kao, C. Y. Chang, C. R. Jeng, P. S. Tsai, V. F. Pang, H. Y. Chiou, J. Y. Peng, I. C. Cheng, and H. W. Chang. 2017. Evaluation and Comparison of the Pathogenicity and Host Immune Responses Induced by a G2b Taiwan Porcine Epidemic Diarrhea Virus (Strain Pintung 52) and Its Highly Cell-Culture Passaged Strain in Conventional 5-Week-Old Pigs. Viruses. 9(5):121-135.
  8. Hung L. C. and I. C. Cheng. 2017. Versatile carboxyl-terminus of capsid protein of porcine circovirus type 2 were recognized by monoclonal antibodies with pluripotency of binding. Mol. Immunol. 85:100-110. (SCI)
  9. Hung L. C., C. Y. Yang, and I. C. Cheng. 2017. Peptides mimicking viral proteins of porcine circovirus type 2 were profiled by the spectrum of mouse anti-PCV2 antibodies. BMC Immunol. 18(25):18-25. (SCI)
  10. Chen K. Y., I. C. Cheng, and C. H. Wang*. 2016. Immunochromographic Strip Using Baculovirus Expression Nucleoprotein to Detect Avian Influenza Antibody. 台灣農學會報 (Journal of the Agricultural Association of Taiwan). 17(1):76-86.
  11. Hung L. C., Y. H. Huang, Y. S. Lai, W. C. Lee, Y. L. Lin, and I. C. Cheng*. 2016. Humoral Immunity of TLRI Black Pig and the Effect of PCV2 subunit vaccination into It [畜試黑豬之體液免疫及接種環狀病毒次單位疫苗之研究]. 中國畜牧協會會誌 (J. Chin. Soc. Anim. Sci.). 45(3):245-261.
  12. Yang C., Y. C. Chang, C. Y. Chang, P. S. Tsai, C. R. Jeng, V. F. Pang, I. C. Cheng, and H. W. Chang. 2016. Identification of a highly transfectable cell line permissive to PEDV infection and replication. Taiwan Vet J. 42(4):187-193.
  13. Huang Y.P., Wang C.H., and I.C. Cheng*. 2013. Monitoring of Avian Influenza Virus in Imported Poultry Products during Year 2005-2008. Taiwan Vet. J. 39(3): 166-173.
  14. Hong H.W., I.C. Cheng, H.W. Chen, and C.H. Wang*. 2012. Comparison of NP and M Primers for Avian Influenza Virus Detection by Reverse Transcription Polymerase Chain Reaction. Taiwan Vet J. 38(4):213-220.
  15. Chen, H.W., Wang, C.H., *Cheng, I.C. 2011 (April)：A type-specific blocking ELISA for the detection of infectious bronchitis virus antibody. J. Virol. Methods 173:7–12 （SCI）
  16. Yang, S.Y., Wang, W.C., Lan, C.B., Chen, C.H., Chieh, J.J., *Horng, H.E., Hong, Chin-Yih, Yang, H.C., Tsai, C.P., Yang, C.Y., Cheng I.C., Chung W.C. 2010 (March)：Magnetically enhanced high-specificity virus detection using bio-activated magnetic nanoparticles with antibodies as labeling markers. J. Virol. Methods 164:14–18 （SCI）
  17. Chen, S.P., Sun, Y.F., Lee, M.C., Cheng, I.C., Yang, P.C., Huang, T.S., Jong, M.H., Robertson, I. D., Edward, J. R., *Ellis, T. M. 2008 (1 January)：Immune responses to foot-and-mouth disease virus in pig farms after the 1997 outbreak in Taiwan. Vet. Microbiol. 126（1-3）:82–90. （SCI）
  18. Chen, S.P., Lee, M.C., Sun, Y.F., Cheng, I.C., Yang, P.C., Lin, Y.L., Jong, M.H., Robertson, I. D., Edward, J. R., *Ellis, T. M. 2007 (May 30)：Immune responses of pigs to commercialized emulsion FMD vaccines and live virus challenge. Vaccine. 25（22）:4464–4469. （SCI）
  19. Kim, S.A., Liang, C.M., Cheng, I.C., Cheng, Y.C., Chiao, M.Y., Tseng, C.J., Lee, F., Jong, M.H., *Liang, S.-M. 2006：DNA Vaccination against Foot-and-Mouth Disease via Electroporation : Study of Molecular Approaches for Enhancing VP1 Antigenicity. The Journal of Gene Medicine 8（9）:1182-1191. （SCI）
  20. *Cheng, I.C., Liang, S.M., Tu, W.J., Chen, C.M., Lai, S.Y., Cheng, Y.C., Lee, F., Huang, T.S., Jong, M.H. 2006：Study on the Porcinophilic Foot-and-Mouth Disease Virus. I. Production and Characterization of Monoclonal Antibodies against VP1. Journal of Veterinary Medical Science 68（8）:859-864. （SCI）
  21. 李明昌、鄭益謙、蔡清恩、林有良、陳靜美、鍾明華、*陳世平。 2004：口蹄疫母體移行抗體對仔牛疫苗免疫反應之影響。 台灣獸醫誌 30（3）:200-205.
  22. Liao, C.W., Cheng, I.C., Yeh, K.S., Lin, F.Y., *Weng, C.N. 2001： Release characteristics of microspheres prepared by co-spray drying Actinobacillus pleuropneumoniae antigens and aqueous ethyl-cellulose dispersion. J. Microencapsulation 18(3）:285-297. （SCI）
  23. *朱瑞民、 楊平政、 鄭益謙。 1997： 綜說：口蹄疫。 中華獸醫誌 23：477-491.
  24. Chesnut, K., She, J.-X., Cheng, I.C., Muralidharan, K., *Wakeland, E.K., 1993： Characterizations of Candidate Genes for IDD Susceptibility from the Diabetes-prone NOD Mouse Strain. Mammalian Genome 4:549-554.（SCI）
  25. 鄭益謙, 朱瑞民。 1990： 豬腸繫膜淋巴結內淋巴球於體內之運轉。 中華獸醫誌 16:365-374.
  26. *Wakeland, E.K., Boehme, S., She, J.-X., Lu, C.-C., McIndoe, R.A., Cheng, I.C., Ye, Y., Potts, W.K., 1990： Ancestral Polymorphisms of MHC Class II Genes: Divergent Allele Advantage. Immunologic Research 9:123.（SCI）
  27. *Siegelman, M.H., Cheng, I.C., Weissman, I.L., Wakeland, E.K., 1990： The Mouse Lymph Node Homing Receptor is Identical with the Lymphocyte Cell Surface Marker Ly-22: Role of the EGF Domain in Endothelial Binding. Cell 61:611-622.（SCI）
2021/08/15 下午11:08

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