王儷蒨 副教授

臨床暨分子醫學研究室(獸二館702室)

王儷蒨實驗室網站:https://sites.google.com/view/wlclab/

姓名:王儷蒨

職稱:副教授

研究領域:微生物分子與遺傳基因診斷學、病毒致病機轉與疫苗研發、動物臨床醫學、動物行為醫學

擔任課程:小動物行為醫學、獸醫臨床及影像診斷學、小動物內科學、人畜共同傳染病、臨床討論、專題討論

聯絡電話:(02)2739-6828 ext. 4270

E-mail:lcwang@ntu.edu.tw

學歷:國立台灣大學獸醫學博士 (2008)

   台北市立動物園臨床獸醫師 (1999-2011)

Office hours:請同學以Email方式與老師預約時間

本研究室竭誠歡迎生物醫學相關科系(非獸醫學系)碩士、獸醫學基礎組碩士、獸醫學臨床組碩士報考加入我們博士班的研究團隊!!!

近期學術著作:(* First or corresponding author)

  • 一、期刊論文

    1. Wang, L.C.*, Kuo, Y.T., Chueh, L.L., Huang, D., Lin, J.H. 2017. The detection and differentiation of canine respiratory pathogens using oligonucleotide microarrays. J Virol Methods (Accepted. In press)
    2. Lin, C.H., Lo, P.Y., Tsai, H.J., Wang, L.C., Liaw, B.S., Hsieh, O.F., Chang, Y.S., Tsai, Y.C., Yu, S.C., Chueh, L.L. 2017. Dirofilaria immitis exposure status in client-owned cats with or without lower airway/lung-associated signs: case-control study in a canine heartworm-endemic area. J Feline Med Surg 19, 153-157.
    3. Wang, L.C.*, Hsu, W.E., Thong, W, Chao, Y.T., Wang, C.H. 2017. Low specificity of a nested reverse transcription polymerase chain reaction to detect avian influenza virus nucleoprotein gene. Taiwan Vet J 43, 1-5.
    4. Wang, L.C.*, Huang, D., Chen, H.W. 2016. Simultaneous subtyping and pathotyping of avian influenza viruses in chickens in Taiwan using reverse transcription loop-mediated isothermal amplification and Microarray. J Vet Med Sci 78, 1223-1228.
    5. Shih, H.Y., Yu, J.F., Wang, L.C.* 2016. Stereotypic behaviors in bears. Taiwan Vet J 42, 1-7.
    6. Yu, Z.A., Liu, C.Y., Pu, C.E., Chen, C.T., Chao, C.H., Yu, J.F., Wang, L.C.* 2015. Investigation of Toxoplasma gondii infection in animals in Taipei Zoo using semi-nest polymerase chain reaction. TW J of Biodivers 18, 19-28.
    7. Cheng, Y.L., Wang, L.C.* (contributed equally as the first author), Wang C.H. 2015. Immunochromatographic strip assay development for a avian influenza antibody detection. Jpn J Vet Res 63, 183-190.
    8. Wang, L.C.*, Huang, D. 2015. Highly sensitive H7N9 Avian influenza virus detection using reverse transcription loop-mediated isothermal amplification and oligonucleotide microarray. Taiwan Vet J 41, 251-255. 
    9. Wang, L.C.*, Lin, D.Y., Thong, W., Wang, C.H. 2015. Multiplex reverse transcription polymerase chain reaction for chicken tumor virus detection. Taiwan Vet J 41, 245-249.
    10. Kang, C.L., Yu, J.F., Lai, H., Gao, J.C., Wang, L.C.* 2015. Retrospective study of the medical status of 34 Formosan sika deer (Cervus nippon taiouanu) at the Taipei Zoo from 2003 to 2014. Korean J Vet Res 55, 169-173.
    11. Lin, H.T., Wang, C.H., Chueh, L.L., Su, B.L., Wang, L.C.* 2015. Influenza A(H6N1) virus in dogs, Taiwan. Emerg Infect Dis 21, 2154-2157. 
    12. Lin, H.T., Hsu, C.H., Tsai, H.J., Lin, C.H., Lo, P.Y., Wang S. L., Wang L.C.* 2015. Influenza A plasma and serum virus antibody detection comparison in dogs using blocking enzyme-linked immunosorbent assay. Vet World 8, 580-583.
    13. Hsieh, P., Yu, J.F., Wang, L.C.* 2015.A Retrospective study of medical status on 63 Affrican hedgehogs (Atelerix albiventris) at the Taipei Zoo from 2003 to 2011. J Exot Pet Med 24, 105-111.
    14. Wang, L.C.*, Huang, D., Cheng, M.C., Lee, S.H., Wang, C.H. 2015. H5 avian influenza virus pathotyping using oligonucleotide microarray. J Virol Methods 220, 39-42.
    15. Wang, L.C.*, Huang, D., Pu, C.E., Wang, C.H. 2014. Avian oncogenic virus differential diagnosis in chickens using oligonucleotide microarray. J Virol Methods 210, 45-50.
    16. Hu, Y.I., Yu, J.F., Guo, J.C., Wang, L.C.* 2014. Detection of antibody against influenza A virus in non-human primates at Taipei Zoo. Taipei Zoo Bulletin 25, 1-6.
    17. Lin, H.T., Wang, C.H., Wu, W.L., Chi, C.H., Wang, L.C.* 2014. Natural A(H1N1)pdm09 influenza virus  infection case in a pet ferret in Taiwan. Jpn J Vet Res 62, 181-185.
    18. Yu, J.F., Lien, C.Y., Wang, L.C.* 2014. Comparison of xylazine-ketamine and dexmedetomidine-ketamine anesthesia in captive Formosan serows (Capricornis swinhoei). J Zoo Wildl Med 45, 787-791.
    19. Wang, L.C.*, Ho, H.P., Yu, J.F. 2014. A 20-year disease survey of captive Formosan serows (Capricornis swinhoei) at the Taipei Zoo (1991-2011). J Zoo Wildl Med 45, 487-491.
    20. Tsai, C.Y., Yu, J.F., Wang, Y.W., Fan, P.C., Cheng, T.Y., Wang, L.C.* 2014. An alternative staining method for counting red eared slider turtle (Trachemys scripta) blood cells using crystal violet in cells diluted with 0.45% sodium chloride. J Vet Diagn Invest 26, 610-615.
    21. Wu, N.H., Tsai, W.T., Chen, H.W., Wang, L.C., Wang, C.H. 2013.Detection of anti-reticuloendotheliosis virus antibody by blocking enzyme-linked immunosorbent assay with expression envelope protein. Avian Dis 57, 72-75.
    22. Wang, L.C.*, Lu, Y.P., Huang, D., Yu, J.F. 2013. Establishment of Polymerase Chain Reaction for the detection of Chlamydophila spp. in koalas (Phascolarctos cinereus). Taipei Zoo Bulletin 24, 1-8.
    23. Chen, Y.T., Tsao, Z., Chang, S.T., Juang, R.H., Wang, L.C., Wang, C.H. 2012. Development of an Antigen-Capture Enzyme-Linked Immunosorbent Assay Using Monoclonal Antibodies for Detecting H6 Avian Influenza Viruses. J Microbiol Immunol Infect 45, 243-247.
    24. Wang, L.C.*, Chang, P.L., Yu, J.F. 2012. The Treatment and Prevention of self-mutilation in Kept Fat-tailed Dwarf Lemurs (Cheirogaleus medius) in Taipei Zoo. Taipei Zoo Bulletin 23, 69-74.
    25. Wang, L.C.*, Huang, D., Chen, C.T., Yu, J.F., Chao, C.H., Pu, C.E. 2012. Detection of Retrovirus gene in Koalas (Phascolarctos cinereus) in Taipei Zoo using Polymerase Chain Reaction. Taipei Zoo Bulletin 23, 25-32.
    26. Lee, J.C.I., Tsai, L.C., Hwa, P.Y., Chan, C.L., Huang, A., Chin, S.C., Wang, L.C., Lin, J.T., Linacre, A., Hsieh, H.M. 2010. A novel Strategy for avian species and gender identification using the CHD gene. Mol Cell Probes 24, 27-31.
    27. Wang, L.C.*, Lin, S., Chin, S.C. 2009. Case report: Hypothyroidism in fat-tailed dwarf lemur (Cheirogaleus medius) at Taipei Zoo. Taipei Zoo Bulletin 21, 89-92.
    28. Lee, J.C.I., Tsai, L.C., Huang, M.T., Jhuang, J.A., Yao, C.T., Chin, S.C., Wang, L.C., Linacre, A., Hsieh, H.M. 2008. A novel strategy for avian species identification by cytochrome b gene. Electrophoresis 29, 2413-2418.
    29. Wang, L.C.*, Pan, C.H., Severinghaus, L.L., Liu, L.Y., Chen, C.T., Pu, C.E., Huang, D., Lir, J.T., Chin, S.C., Cheng, M.C., Lee, S.H., Wang, C.H. 2008. Simultaneous detection and differentiation of Newcastle disease and avian influenza viruses using oligonucleotide microarrays. Vet Microbiol 127, 217-226.
    30. Wang, L.C.* Severinghaus, L.L., Chen, C.T., Liu, L.Y., Pan, C.H., Huang, D., Lee, H.Y., Lir, J.T., Chin, S.C., Pu, C.E., Wang, C.H. 2008. Sex identification of owls (Family Strigidae) using oligonucleotide microarrays. J Hered 99, 187-192.
    31. Wang, L.C.*, Chen, C.T., Severinghaus, L.L., Chin, S.C., Pu, C.E., Wang, C.H. 2007. Avian sexing using multiplex PCR- a more precise and simplified method. Taipei Zoo Bulletin 19, 45-60.
    32. Wang, L.C.*, Chen, C.T., Lee, H.Y., Li, S.H., Lir, J.T., Chin, S.C., Pu, C.E., Wang, C.H. 2007. Sexing a wider range of avian species based on two CHD1 introns with a unified reaction condition. Zoo Biol 26, 425-431.
    33. Wang, L.C.*, Chen, C.T., Lee, H.Y., Li, S.H., Lir, J.T., Chin, S.C., Pu, C.E., Wang, C.H. 2006. Cut feather containing rachis as a sampling way for avian sexing. Zoo Biol 25, 279-283.
    34. Wang, L.C.*, Lu, Y.T., Chen, T.Y., Chin, S.C. 2006. Helicobacter pylori in captive serval (Leptailarus serval). Taipei Zoo Bulletin 18, 1-6.
    35. Wang, L.C.*, OuYanh, E.H., Huang, W.C., Lin, Y.H., Chin, S.C. 2005. Acupuncture treatment of limb paralysis in an African hedgehog (Atelerix albiventris). Taipei Zoo Bulletin 17, 55-62.
    36. Wang, L.C.*, Liu, C.H., Chang, P.H., Chen, T.Y., Lu, Y.T., Chin, S.C. 2004. Adrenal gland tumors in two captive ferrets (Mustela putorius furo). Taipei Zoo Bulletin 16, 25-33.
    37. Chin, S.C., Lam, L., Lin, K.W., Wang, L.C.* 2003. Investigation of renal insufficiency of Bengal tigers (Panthera tigris) at Taipei zoo. Taipei Zoo Bulletin 15, 51-59.
    38. Chin, S.C, Wang, L.C., Chen, C.T., Law, Y.J., Wang, S., Wang, I.P.J., Pu, C.E., Li, S.H. 2002. Sex identification of king penguin (Aptenodytes patagonicus). Taipei Zoo Bulletin 14, 51-57.
    39. Chin, S.C., Wu, F.C., Wang, L.C., Chao, C.H., Chen, M.Y., Pu, C.E. 2001. Blood relationships determination of chimpanzee population at Taipei city zoo by the STR loci genotypes analysis. Taipei Zoo Bulletin 13, 51-59.
    40. Yang, J.L., Wang, L.C., Chang, C.Y., Liu, T.Y. 1999. Singlet oxygen is the major species participating in the induction of DNA strand breakage and 8-hydroxydeoxyguanosine adduct by lead acetate. Environ Mol Mutagen 33,194-201.

    二、研討會論文

    1. Hsu, W.E., Wang, L.C., and Wang, C.H. 2016. Infection Potential Analysis of the Dog H6N1 Influenza Virus in Vitro.中華民國獸醫學會暨臺灣省畜牧獸醫協會105年度秋季學術論文研討會暨全國人畜共通傳染病研討會議. P.24.

    2. Yu, J.F., Chang, Y.J., Tsai, D.W., Xue, Y.J., Li, R.H., Wang, L.C. 2016. Semen cryopreservation in Great apes: Animal training and improvement in spermatozoa quality. The 9th International Meeting of Asian Society of Conservation Medicine (ASCM). Taipei, Taiwan. p.59.
    3. Wang, L.C.* 2015. Case report: cat self-mutilated overgrooming. 3rd Annual International Conference on Advances in Veterinary Science research. Bangkok, Thailand. p.11.
    4. Yu, J.F., Chin, S.C., Wang, L.C. 2014. Hand-rearing of a rescued baby Malayan pangolin (Manis javanica). The 22nd SEAZA annual conference. Taipei, Taiwan. p.25.
    5. Wang, L.C.* 2014. A 20-year disease survey of captive Formosan serows (Capricornis swinhoei) at the Taipei Zoo (1911-2011). The 22nd SEAZA annual conference. Taipei, Taiwan. p.8.
    6. Kuo, Y.T., Wang, L.C., Chueh, L.L. 2014. The detection and differentiation of canine respiratory pathogens using gene chip. 中華民國獸醫學會103年度年度春季學術研討會. p.30.
    7. Lin, H.T., Wang, C.H., Chueh, L.L., Tsai, H.J., Lin, C.H., Lo, P.Y., Wang, S.L., Wang, L.C.* 2014. Seroprevalence investigation of influenza A virus in dogs and cats in Taiwan.中華民國獸醫學會103年度年度春季學術研討會. p.29.
    8. Wang, L.C.*, Len, C.Y., Yu, J.F. 2013. Case report: mammary gland adenocarcinoma in a Malayan porcupine (Acanthion brachyura). Proceedings of 2013 Federation of Asian Veterinary Associations (FAVA) congress, Taipei, Taiwan. p.180.
    9. Wang, L.C.*, Chin, S.C. 2012. Case Report: squamous cell carcinoma in external aural canal of a llama (Lama Glama). 中華民國獸醫學會暨臺灣省畜牧獸醫協會101年聯合年會暨學術論文發表會. P.76.
    10. Wang, L.C.*, Len, C.Y., Chin, S.C., Shih, L.L., Yang, C.J. 2010. Diagnosis of adrenal gland hyperplasia in a captive Chinese mink (Mustela sibirica taivana) using fecal glucocorticoid assay and computer tomography. American Association of Zoo Veterinarians. South padre Island, Texas, USA.
    11. Wang, L.C.*, Huang, D., Pan, C.H., Liu, L.Y., Chen, C.T., Chin, S.C., Wang, C.H. 2009. Simultaneous detection of avian influenza and Newcastle disease viruses using multiplex PCR on fecal samples of wild birds in Taipei Zoo. The 3rd international workshop of Asian society of zoo and wildlife medicine. Seoul. Korea.
    12. Wang, L.C.*, Yang, C.J., Yu, J.F. 2009. Acupuncture in a Bengal tiger (Panthera tigris tigris) with hindlimb paralysis. The international conference on diseases of zoo and wild animals. Hilvarenbeek, The Netherlands.
    13. Wang, L.C.*, Chin, S.C., Chang, J.H., Yang, C.J., Chen, P.C., Severinghaus, L.L., Lir, J.T., Wang, C.H. 2007. Helicobacter infection in captive serval (Leptailarus serval). International Symposium on Diseases of Zoo and Wild Animals. Edinburgh, Scotland, UK.
    14. Wang, L.C.*, Wang, C.H. 2007. Detection and differentiation of Newcastle disease using oligonucleotide microarray. 中華民國獸醫學會暨臺灣省畜牧獸醫協會九十六年聯合年會暨學術論文發表會。台中,台灣。
    15. Wang, L.C.*, Chen, C.T, Lir, J.T., Chin, S.C., Pu, C.E., Wang, C.H. 2006. Molecular sexing of Nicobar pigeons (Caloenas nicobarica) from feather rachis. American Association of Zoo Veterinarians. Tampa, Florida, USA.
    16. Wang, L.C.* 2004. Case report: The hyperplasia and neoplasia of adrenal glands in cative ferrets (Mustela putorius furo).The 12th South East Asian Zoos Association. Hong Kong, China.
    17. Wang, L.C.*, Chin, S.C. 2003. Sex identification of king penguin. (Aptenodytes patagonicus).The 13th South East Asian Zoos Association. Hong Kong, China.

    三、書及專書論文

    1. 王儷蒨。2011年。兔子常見的疾病與醫療。動物園雜誌
    2. 王儷蒨。2008年。蜜袋鼯疾病診斷與防治。動物疫病診斷鑑定研習會手冊
    3. 王儷蒨。2008年。雪貂疾病診斷與防治。動物疫病診斷鑑定研習會手冊
    4. 王儷蒨。2008年。鳥類常見之人畜共同傳染病。97年度鳥類救傷及實務操作研習營手冊
    5. 王儷蒨、余珍芳、郭俊成、王寶榮、張志華。2003年。臺北市立動物園野生靈長類動物麻醉手冊
    6. 王儷蒨。2003年。黑猩猩族群血緣分析研究。動物園雜誌
    7. 金仕謙、吳芳親、王儷蒨、趙齊相、陳孟宜、蒲長恩。2000年。臺北市立動物園黑猩猩族群STR血緣分析之研究 DNA多型性分析鑑識運用研討會論文集

    四、研究計畫

    1. 乳酸益生菌對狗情緒異常治療效果的評估 (2016/10/01-2018/9/30)(研究合作。陽明大學/益福生醫股份有限公司)
    2. 發展禽流感類病毒顆粒疫苗同步對抗台灣新型與舊型禽流感病毒 (2017/01/01-2019/12/31)(主持。中央研究院)
    3. 室內空氣品質(二手菸等)對呼吸系統與心血管功能影響之自發疾病動物模式: 以與其人類飼主曝露於相同室內空污環境下之伴侶動物為追蹤研究對象 (2015/07/01-2017/07/31)(共同主持。科技部)
    4. 新發生家禽白血病J亞群病毒的分子流行病學探討 (2015/08/01-2017/07/31)(主持。科技部)
    5. 犬呼吸道病原偵測及分型基因晶片之研發 (2015/06/01-2016/05/31)(主持。科技部)
    6. 貓傳染性腹膜炎發病相關宿主因子之鑑定 (2014/08/01-2015/07/31)(主持。科技部)
    7. 以環狀等溫增幅與生物晶片系統快速檢測與鑑別診斷家禽流行感冒病毒H5N2、H6N1與H7N9 (2013/11/01-2015/10/31)(主持。科技部)
    8. 鑑別診斷高病原性與低病原性禽流感病毒暨重要家禽腫瘤性病毒之寡核酸微陣列檢測系統的開發 (2013/02/01-2013/12/31)(主持。科技部)
    9. 野生動物重要傳染性疾病之分子診斷 (2012/01/01-2012/12/31)(主持。台北市立動物園)

    五、專利

    1. 2016年,用於鑑別H5禽流戚病毒病原性之寡核酸探針合其之套組及方法,中華民國18年專利 (發明第 I 531654號)
    2. 2012年,AVIAN SEX IDENTIFICATION OLIGONUCLEOTIDES,美國20年專利 (No. 12/339, 178)
    3. 2012年,於鳥類性別鑑定的寡核苷酸,中華民國16年專利 (發明第I 372784 號) 

2015/01/31 下午21:15

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