林辰栖 教授 (兼任人畜共通傳染病研究中心主任)
姓名:林辰栖
職稱:教授
研究領域:腫瘤生物學、臨床病理學、微生物學、免疫學
擔任課程:癌症生物及免疫學特論、獸醫臨床病理學及實習、細胞分子生物學、獸醫細菌學及實習、獸醫生理學及實習
聯絡電話:02-3366-1286
E-mail:cslin100@ntu.edu.tw
學歷:交通大學生物科技研究所理學博士
Office hours:請同學先以Email方式與老師約定時間
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※ 鼓勵跨領域學習,歡迎非獸醫、生命科學、與生物醫學領域的同學加入我們的研究行列!

近期學術著作:
◎ 期刊論文:
* Corresponding author- Wu C. F., C. H. Chen, C. Y. Wu, C. S. Lin , Y. C. Su, C. F. Wu, H. P. Tsai, P. S. Fan, C. H. Yeh, W. C. Yang, and G. R. Chang. 2020. Quinolone and organophosphorus insecticide residues in bivalves and their associated risks in Taiwan. Molecules. 25(16): 3636. (SCI)
- Hsu C. P., C. S. Lin , C. H. Fan, N. Y. Chiang, C. W. Tsai, C. M. Chang, and I. L. Liu. 2020. Geometric accuracy of an acrylonitrile butadiene styrene canine tibia model fabricated using fused deposition modelling and the effects of hydrogen peroxide gas plasma sterilization. BMC Vet. Res. 16(1): 478. (SCI)
- Hsu C. H., H. Tomiyasu, J. J. Lee, C. W. Tung, C. H. Liao, C. H. Chuang, L. Y. Huang, K. W. Liao, C. H. Chou, A. T. Liao, and C. S. Lin . 2020. Genome-wide DNA methylation analysis using MethylCap-seq in canine high-grade B-cell lymphoma. J. Leukoc. Biol. doi: 10.1002/JLB.2A0820-673R. (SCI)
- Wu C. F., P. H. Hou, C. Mao, Y. C. Su, C. Y. Wu, W. C. Yang, C. S. Lin , H. P. Tsai, H. J. Liao, and G. R. Chang. 2020. Mirtazapine reduces adipocyte hypertrophy and icreases glucose transporter expression in obese mice. Animals. 10(8): 1423. (SCI)
- Xiu Y. F., C. C. Liu, S. H. Xu, C. S. Lin , and C.C. Chou. 2020. The genetic diversity and population genetic structure of the Red Panda, Ailurus fulgens, in Zoos in China. Animals. 10(6): 1008. (SCI)
- Kao P. H., C. H. Chen, Y. W. Tsang, C. S. Lin , H. C. Chiang, C. C. Hunag, M. S. Chi, K. L. Yang, W. T. Li, S. J. Jao, C. A. Minnaar, K. H. Chi, and Y. S. Wang. 2020. Relationship between energy dosage and apoptotic cell death by modulated electro-hyperthermia. Sci. Rep. 10: 8936. (SCI)
- Liu I. L., T. F. Chung, W. H. Huang, C. H. Hsu, C. C. Liu, Y. H. Chiu, K. C. Huang, A. T. Liao, and C. S. Lin . 2020. Kynurenine 3-monooxygenase (KMO), and signal transducer and activator of transcription 3 (STAT3) expression is involved in tumour proliferation and predicts poor survival in canine melanoma. Vet. Comp. Oncol. doi: 10.1111/vco.12641. (SCI)
- Kuo I. M., J. J. Lee, Y. S. Wang, H. C. Chiang, C. C. Huang, P. J. Hsieh, W. Han, C. H. Ke, A. T. Liao, and C. S. Lin . 2020. Potential enhancement of host immunity and anti-tumor efficacy of nanoscale curcumin and resveratrol in colorectal cancers by modulated electro- hyperthermia. BMC Cancer. 20(1): 603. (SCI)
- Huang Y. Y., C. H. Chen, C. H. Hsu, T. Y. Kuo, C. C. Liu, A. T. Liao, and C. S. Lin . 2020. Inhibiting autophagy potentiates the antitumor efficacy of Euphorbia royleana for canine mammary gland tumors. BMC Vet. Res. 16(1): 193. (SCI)
- Ho S. Y., P. R. Chen, C. H. Chen, N. M. Tsai, Y. H. Lin, C. S. Lin , C. H. Chuang, X. F. Huang, Y. L. Chan, Y. K. Liu, C. H. Chung, S. L. Weng, and K. W. Liao. 2020. Lipoplex-based targeted gene therapy for the suppression of tumours with VEGFR expression by producing anti-angiogenic molecules. J. Nanobiotechnol. 18(1): 58. (SCI)
- Liu C. C., L. T. Chang, T. F. Chuang, and C. S. Lin* . 2020. Characteristics of major histocompatibility complex expression and cytokine profiles in spontaneous canine tumours. Taiwan Vet. J. 46(1): 7-20.
- Chen H. Y., C. C. Liu, B. H. Liu, and C. S. Lin* . 2020. Expression of canine kynurenine 3-monooxygenase by baculovirus for canine mammary tumor diagnosis. Pak. Vet. J. 40(2): 145-150. (SCI)
- Chiu Y. H., Y. Y. Lee, K. C. Huang, C. C. Liu, and C.S. Lin* . 2019. Dovitinib Triggers Apoptosis and Autophagic Cell Death by Targeting SHP-1/p-STAT3 Signaling in Human Breast Cancers. J. Oncol. doi: 10.1155/2019/2024648. (SCI)
- Chiu Y. H., H. J. Lei, K. C. Huang, Y. L. Chiang, and C. S. Lin* . 2019. Overexpression of Kynurenine 3-Monooxygenase Correlates with Cancer Malignancy and Predicts Poor Prognosis in Canine Mammary Gland Tumors. J. Oncol. doi: 10.1155/2019/6201764. (SCI)
- Lee J. J., H. Y. Lin, C. A. Chen, C. S. Lin , and L. C. Wang. 2019. Development of oligonucleotide microarray for simultaneous detection of two canine MDR1 genotypes and the association with chemotherapy side effects. J. Vet. Sci. 20(1): 27-33. (SCI)
- Yang J. D., H. Y. Huang, M. Y. Chiu, C. H. Hsu, S. Shrestha, M. C. Wu, C. S. Lin* , and H. D. Huang. 2019. Genome-wide methylome analysis using methylcap-seq uncovers novel methylated markers for canine lymphoma CLBL-1. Taiwan Vet J. 45(3): 1-10.
- Lee J. J., H. Y. Lin, C. A. Chen, C. S. Lin , and L. C. Wang. 2018. The development of oligonucleotide microarray for simultaneous detection of two canine MDR1 genotypes and the association with chemotherapy side effects. J. Vet. Sci. 2018 Nov 26. [Epub ahead of print] (SCI)
- Lin C. S.* , C.P. Chang, C. S. Chiang, T. F. Chiang, C. H. Hsu, and C. C. Liu. 2018. Activating natural killer (NK) cytotoxicity of canine CD5-CD21- cells requires low surface CD5 density NK cells. Iran. J. Vet. Res. 19(2):87-95. (SCI)
- Hsu C. H., I. L Liu., C. C. Liu., B. H. Liu, M. J. Pan, and C. S. Lin* . 2018. Seroepidemiological survey of canine leptospirosis in northern Taiwan during 2008~2015. Taiwan Vet. J. 44(3): 141-149.
- Lin C. S.* , G. H. Chiang, C. H. Liu, H. C. Tsai, K. Chen, S. H. Huang, L. I. Cheng, and C. C. Chou. 2017. Comparison of a full spectrum multianalyte clinical analyzer to six reference instruments using canine and feline blood samples. Veterinarni. Medicina. 62(06): 342–350. (SCI).
- Chen J. T., B. H. Liu, C. H. Hsu, C. C. Liu, A. T. Liao, C. H. Chou, and C. S. Lin*. 2017. Bioaerosol investigation in three veterinary teaching hospitals in Taiwan. Taiwan Vet. J. 43(1): 39-45.
- 1. Tien Y.T., M.H. Chang, P.Y. Chu, C.S. Lin, C.H. Liu, and A.T. Liao*. 2015. Downregulation of the KLF4 transcription factor inhibits the proliferation and migration of canine mammary tumor cells. Vet. J. 205(2):244-53. (SCI)
- Liu C. C., C. S. Lin, T. F. Chuang, and C. T. Lin. 2014. Investigation of 201 cases of canine keratoconjunctivitis sicca in Taiwan. Taiwan Vet. J. 40(2): 89-94.
- Lin S. C., T. F. Chuang, C. S. Lin, D. S. Lin¸ and A. T. Liao. 2014. Immune characterization of peripheral blood mononuclear cells of the dogs restored from inoculation of canine transmissible venereal tumor cells. Taiwan Vet. J. 40(4):181-190.
- Lin CS*, Chen MF, Wang YS, Chuang TF, Chiang YL, Chu RM. 2013. IL-6 restores dendritic cell maturation inhibited by tumor-derived TGF-β through interfering Smad 2/3 nuclear translocation. Cytokine. 62(3):352. (SCI 3.019; 128/290=44.1% in BIOCHEMISTRY & MOLECULAR BIOLOGY)
- Yu HC, Lin CS, Tai WT, Liu CY, Shiau CW, Chen KF*. 2013. Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation. J Biol Chem. 2013 May 15. [Epub ahead of print] (SCI 4.773; 66/290=22.8% in BIOCHEMISTRY & MOLECULAR BIOLOGY)
- (Equal First author)Huang CY, Lin CS, Tai WT, Hsieh CY, Shiau CW, Cheng AL, Chen KF*. 2013. Sorafenib Enhances Radiation-Induced Apoptosis in Hepatocellular Carcinoma by Inhibiting STAT3. Int J Radiat Oncol Biol Phys. 86(3):456. (SCI 4.105; 12/116=10.3% in RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING )
- Tai WT, Shiau CW, Chen HL, Liu CY, Lin CS, Cheng AL, Chen PJ, Chen KF*. 2013. Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells. Cell Death Dis. 7;4:e485. (SCI 5.333; 45/181=24.9% in CELL BIOLOGY)
- Chiang HC, Liao AT, Jan TR, Wang YS, Lei HJ, Tsai MH, Chen MF, Lee CY, Lin YC, Chu RM, Lin CS*. 2013 Gene-expression profiling to identify genes related to spontaneous tumor regression in a canine cancer model. Vet Immunol Immunopathol. 62(3): 352. (SCI 2.076; 10/143=6.9% in VETERINARY SCIENCES)
- Chiang HC, Wang YS, Chou CH, Liao AT, Chu RM, Lin CS*. 2012 Overexpression of chemokine ligand 7 is associated with the progression of canine transmissible venereal tumor. BMC Vet Res. 8(1):216. (SCI 2.0; 13/143=9.1% in VETERINARY SCIENCES)
- Wang CT, Lin CS, Shiau CW, Chu PY, Hsiao CC, Chiang YL, Tai WT, Chen KF*. 2012 SC-1, a sorafenib derivative, shows anti-tumor effects in osteogenic sarcoma cells. J Orthop Res. 2012 Aug 23. doi: 10.1002/jor.22218. [Epub ahead of print] (SCI 2.811; 9/63=14.2% in ORTHOPEDICS)
- Lin CS, Kao SH, Chen YC, Li CH, Hsieh YT, Yang SC, Wu CJ, Lee RP, Liao KW*. 2012 Enhancement of anti-murine colon cancer immunity by fusion of a SARS fragment to a low-immunogenic carcinoembryonic antigen. Biol Proced Online. 14:2. (SCI 1.290; 59/72= 81.9% in BIOCHEMICAL RESEARCH METHODS)
- Yu HC, Hou DR, Liu CY, Lin CS, Shiao CW, Cheng AL, Chen KF*. 2012 Cancerous inhibitor of protein phosphatase 2A mediates bortezomib-induced autophagy in hepatocellular carcinoma independent of proteasome. PLOS One. (Accepted) (SCI 4.092; 12/85=14.1% in BIOLOGY)
- Lin CS, Kao SH, Chen YC, Li CH, Hsieh YT, Yang SC, Wu CJ, Lee RP, Liao KW*. 2012 Enhancement of anti-murine colon cancer immunity by fusion of a SARS fragment to a low-immunogenic carcinoembryonic antigen. Biol Proced Online. 14:2. (SCI 1.290; 59/72 in BIOCHEMICAL RESEARCH METHODS)
- (Equal First author) Liao KW, Lin CS, Chen WL, Yang CT, Lin CM, Hsu WT, Lin YY, Chiu YH, Huang KC, Wu HY, Wu MS, Wu CJ, Mao SJ, Tsai NM*. 2011 Antibodies against Helicobacter pylori heat shock protein 60 aggravate HSP60-mediated proinflammatory responses. Cytokine. 55(2):174-80. (SCI 3.019; 128/289 in BIOCHEMISTRY & MOLECULAR BIOLOGY)
- Yu WY., Chuang TF, Tiernyc CT, Liao AT, Lin CS, Chiou KH, Tsai CL, Liu CH, Lie WC, Fischer L, and Chu RM*. 2011. Chicken HSP70 DNA vaccine inhibits tumor growth in a canine cancer model. Vaccine 29(18):3489-3500. (SCI 3.766; 23/111 in MEDICINE, RESEARCH & EXPERIMENTAL)
- Pai CC, Kuo TF, Mao SJ, Chuang TF, Lin CS, Chu RM*. 2011. Immunopathogenic behaviors of canine transmissible venereal tumor in dogs following an immunotherapy using dendritic/tumor cell hybrid. Vet Immunol Immunopathol. 2011 Feb 15;139(2-4):187-99. (SCI 2.076; 10/143 in VETERINARY SCIENCES)
- Wang CL, Lin CS, Tsai HJ, Hung YP, Chou CH*. 2011. Evaluation the Immune Regulation of Laying Hens Fed by Chitosan. Taiwan Vet J 37 (3): 214-220.
- Lin CS, Wang CL, Tsai HJ, Chou CH*. 2010 Growth of Listeria monocytogenes on a RTE-meat matrix enhances cell invasiveness to Mouse J744A.1 macrophages. International Journal of Food Microbiology. 144:199-201. (SCI 3.327; 9/128 in FOOD SCIENCE & TECHNOLOGY)
- Lin CS, He PJ, Hsu WT, Wu MS, Wu CJ, Shen HW, Hwang CH, Lai YK, Tsai NM, Liao KW*. 2010, Helicobacter pylori-derived Heat shock protein 60 enhances angiogenesis via a CXCR2-mediated signaling pathway, Biochem Biophys Res Commun. 25;397(2):283-9. (SCI 2.484; 39/74 in BIOPHYSICS)
- Lin CS, He PJ, Tsai NM, Li CH, Yang SC, Hsu WT, Wu MS, Wu CJ, Cheng TL, Liao KW*. 2010, A potential role for Helicobacter pylori heat shock protein 60 in gastric tumorigenesis., Biochem Biophys Res Commun, 392(2):183-9. (SCI 2.484; 39/74 in BIOPHYSICS)
- Lin CY, Huang YS, Li CH, Hsieh YT, Tsai NM, He PJ, Hsu WT, Yeh YC, Chiang FH, Wu MS, Chang CC, Liao KW*. 2009, Characterizing the polymeric status of Helicobacter pylori heat shock protein 60., Biochem Biophys Res Commun. 388(2):283-9. (SCI 2.484; 39/74 in BIOPHYSICS)
- Lin CY, Chuang TF, Liao KW, Huang YJ, Pai CC, Chu RM*. 2008, Combined immunogene therapy of IL-6 and IL-15 enhances anti-tumor activity through augmented NK cytotoxicity., Cancer Lett. 272(2):285-95. (SCI 4.238; 42/194 in ONCOLOGY)
- Lin YL, Chen YS, Hsieh JH, Kin CM, Wu HY, Lin CS, Chu RM, Lioa KW, Hsu YH. 2010, Utilization of IκB-EGFP chimeric gene as an indicator to identify microbial metabolites with NF-κB inhibitor activity. Biological Procedures Online 12(1):9033. (SCI 1.290; 59/72 in BIOCHEMICAL RESEARCH METHODS)
- Li CH, Lee, RP, Lin YL, Lin CS, Hsu BG, Jen TF, Chen YC, Liao KW, Yang FL*. 2010, The treatment of propofol induced the TGF-β1 expression in human endothelial cells to suppress endocytosis activities of monocytes. Cytokine 2010 Dec;52(3):203-9. (SCI 3.019; 128/289 in BIOCHEMISTRY & MOLECULAR BIOLOGY)
- Liu CC, Wang YS, Lin CY, Chuang TF, Liao KW, Chi KH, Chen MF, Chiang HC, Chu RM*. 2008, Transient downregulation of monocyte-derived dendritic-cell differentiation, function, and survival during tumoral progression and regression in an in vivo canine model of transmissible venereal tumor., Cancer Immunol Immunother. 2008 Apr;57(4):479-91. (SCI 3.701; 43/139 in IMMUNOLOGY)
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